HORDB

ID: hor004328
Uniprot ID: A0A3B3IP44
Protein name: Substance P
Gene name: tac1
Organism: Oryzias latipes (Japanese rice fish) (Japanese killifish)
Family: Tachykinin family
Source: animal
Expression: Brain
Disease: NA
Comments: NA
Taxonomy: Oryzias (genus), Oryziinae (subfamily), Adrianichthyidae (family), Adrianichthyoidei (suborder), Beloniformes (order), Atherinomorphae (superorder), Ovalentaria, Percomorphaceae, Euacanthomorphacea, Acanthomorphata, Ctenosquamata, Eurypterygia, Neoteleostei, Euteleosteomorpha (cohort), Clupeocephala, Osteoglossocephalai, Teleostei (infraclass), Neopterygii (subclass), Actinopteri (class), Actinopterygii (superclass), Euteleostomi, Teleostomi, Gnathostomata, Vertebrata, Craniata (subphylum), Chordata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: GO:0007217 tachykinin receptor signaling pathway
GO CC: NA

Sequence: KPRPHQFIGLM
Length: 11
Propeptide: MKLLLLLSALVALLTGVRVLCQDPEPKEDADYWTSTNHQDGWLSSEPLREMLLRMTRKPRPHQFIGLMGRRSTGEGCSICVCVCVWMSRSHSMSLFAPTSTLPLPPSSKRTDHQEK
Signal peptide: MKLLLLLSALVALLTGVRVLC
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor004328_AF2.pdb

hor004328_ESM.pdb

Mass:	150217	Formula:	C61H98N18O13S
Absent amino acids:	ACDENSTVWY	Common amino acids:	P
pI:	11.65	Basic residues:	3
Polar residues:	1	Hydrophobic residues:	3
Hydrophobicity:	-51.82	Boman Index:	-1456
Half-Life:	1.3 hour	Half-Life Yeast:	3 min
Half-Life E.Coli:	2 min	Aliphatic Index	70.91
Instability Index:	603.64	Extinction Coefficient cystines:	0
Absorbance 280nm:	0

PubMed ID: 19118555
Title: Mass Spectrometric Map of Neuropeptide Expression and Analysis of the Gamma-Prepro-Tachykinin Gene Expression in the Medaka (Oryzias Latipes) Brain